Elastofibroma of the spine

Elastofibroma of the spine

Due to the huge amount of refugees, coming to Europe from Africa and the Middle East since 2014, there are more rare diseases in Switzerland than before. Not only infectious diseases like tuberculosis of the spine but also tumors are seen, which are more frequent in different ethnic populations.

We diagnosed an elastofibroma in a 28 years old male refugee coming from the Solomon Islands. Diagnose of intraspinal elastofibroma L4/5 was prooven by CT-guided biopsy. After we got the results from the pathologist we had to search the databases and found nine publications while using the terminus „elastofibroma AND spine“ (date of serach: Jan 22nd 2016). 5 of them matched in a sufficient way and we like to post these 5 abstracts.

See our results here:

  1. Pediatr Neurosurg. 2013;49(4):240-2. doi: 10.1159/000363332. Epub 2014 Jun 27.
    Spinal elastofibroma: a case report.
    Miranda Zambrano AD(1), Rivero-Garvía M, Galbarriatu L, Ruíz-Martín L, Márquez-Rivas J.
    Author information: (1)Virgen del Rocío Hospital, Seville, Spain.Elastofibroma is a benign fibroproliferative tumor of unknown origin and pathogenesis. It usually appears in the subscapular or infrascapular area. It is extremely rare in the spinal area, and it is most common in middle-aged women. In most cases, it is asymptomatic. Its diagnosis is based on nuclear MRI, where it presents a homogeneous lesion, similar to the skeletal muscle, hyperintense in T1-weighted sequences and hypointense in T2-weighted sequences. This finding is confirmed with anatomical pathology tests, where it appears as a nonencapsulated lesion made up of wide collagen bands from connective tissue mixed with fat and muscle tissue. The treatment of choice is surgical removal of the lesion. We present a clinical case of elastofibroma, a benign and rare pathology with few described cases in the literature, in a patient with a previous dorsal lesion. © 2014 S. Karger AG, Basel. PMID: 24993647 [PubMed – indexed for MEDLINE]
  2. Int J Surg Pathol. 2010 Dec;18(6):508-15. doi: 10.1177/1066896909339736. Epub 2009 Jul 3.
    Elastofibromatous changes in tissues from spinal biopsies. A degenerative process afflicting a small but important subset of patients operated for spinal canal compression: report of 18 cases.
    Daum O(1), Ferda J, Curik R, Choc M, Mukensnabl P, Michal M.
    Author information: (1)Departments of Pathology, Medical Faculty Hospital, Charles University in Prague.Elastofibroma is a tumorlike lesion occurring usually in the subscapular region of elderly females. In this study, 18 cases of elastofibromatous tissue retrieved from the spinal canal were analyzed to elucidate its frequency and possible clinical associations. The patients included 8 men and 10 women with a mean age of 63.4 years (range, 40-84 years). The elastic nature of the material was confirmed by Weigert’s elastic stain and immunohistochemically. Elastofibroma was diagnosed in 6 patients, and elastofibroma-like tissue was found in 11 samples. The finding of elastofibromatous tissue was associated with clinical diagnosis of juxtaarticular cysts (3 cases), thickening of ligamentum flavum (4 cases), extradural expansion (2 cases), metastatic involvement of the dorsal spine (3 cases), and a vertebral fracture (1 case). Two cases were located above the transpedicular fixation. Elastofibromatous tissue may be found in approximately 2.6% of all spinal biopsies and it may take part in compression of spinal cord and nerve roots. PMID: 19578045 [PubMed – indexed for MEDLINE]
  3. Int J Surg Pathol. 2010 Feb;18(1):75-6. doi: 10.1177/1066896909355811.
    Elastofibroma in ligamentum flavum in a patient with symptoms of spinal stenosis: yet another case report.
    Petersson F.
    PMID: 20106830 [PubMed – indexed for MEDLINE]
  4. Rofo. 2002 Dec;174(12):1577-8.
    [A case of spinal elastofibroma]. [Article in German]
    Köhler P(1), Kind M, Stengele O.
    Author information: (1)Konstanz, Germany.
    PMID: 12471532 [PubMed – indexed for MEDLINE]
  5. Spine (Phila Pa 1976). 1983 Oct;8(7):800-2.
    Intraspinal elastofibroma. A case report.
    Prete PE, Henbest M, Michalski JP, Porter RW.
    PMID: 6665583 [PubMed – indexed for MEDLINE]